Presentations

Prepared by: Chelsea L. Rahiman, Roberto A. Ribas, Chang Liu, Julia An, Patrick J. McCann, Manan Vij, Jason Cham, Rosa Martín-Pérez, Ariel Chen, Parin Shah, Aleksandar Z. Obradovic, Simon Cheng, Ramon C. Sun, Catherine S. Spina

This poster integrates spatial metabolomics and single-nuclear RNA sequencing to investigate metabolism and immune regulation in NSCLC tumors, revealing how adenosine signaling drives immune suppression and uncovering potential new therapeutic targets.

Prepared by: Krishan K. Saini, Samanta Sarti, Chelsea L. Rahiman, Brian E. Ragaishis, Patrick J. McCann, Shruti Bansal, Jason Cham, Julia An, Rosa Martin, Ariel Chen, Catherine S. Spina

This poster explores how radiation affects immune responses and adenosine signaling in lung cancer, offering insights to improve future immuno-radiotherapy approaches.

Prepared by: Shruti Bansal, Samantha Sarti, Namita Sen, Chelsea Rahiman, Brian Ragaishis, Lindsay Caprio, Benjamin Izar, Catherine Spina

This poster explores how tumor- and host-derived adenosine affect radiosensitivity in breast cancer models. It shows that radiation increases adenosine levels, and that loss of CD73 in tumor—but not host—cells improves response. Targeting CD73 and adenosine receptors may enhance tumor control.